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Biophysics
Textbook On-Line
A
number of book chapters and Biophysical Journal teaching articles presently
available in PDF or html format (about 20). Sponsored by the Biophysical
Society. |
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GLACTONE
Glactone
is a three year project funded by the Chancellor of the University System of
Georgia. The goal of this project to provide computer based resources for
chemistry and biochemistry students and faculty in the State of Georgia.
There are currently 9 colleges and universities making up Glactone, with
Georgia State University being the lead institution. |
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Introduction
to Macromolecular Simulation
The
purpose of this tutorial is to introduce several popular numerical
techniques used to simulate the structure and dynamics of biomolecules. The
discussion is confined to simulation methods that apply classical mechanics
to biological systems, although some quantum theory is presented to quantify
some shortcomings of classical approximations. Molecular dynamics (MD)
simulation, Langevin dynamics (LD) simulation, Monte Carlo (MC) simulation,
and normal mode analysis are among the methods surveyed here. |
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Physics
of biological processes
This
is a physics hypertext book: it is intended as a vehicle for students in the
biological and chemical sciences, enabling them to understand the physical
underpinnings of their later studies. As often as possible, the systems
under investigation will relate to human physiology, for there is no
substitute for relevance to motivate the study of a subject.
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Encyclopedia
of Analytical Instrumentation (Science Hypermedia, Inc.)
Books,
Journals, Software, and other Resources / Data Acquisition and Electronics /
Data Handling / Diffraction / Electrochemistry / Gravimetry / Imaging / Mass
Spectrometry / Materials & Surface Analysis / Optics / Sensors /
Separations / Spectroscopy / Standards / Thermal Methods / Titration
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The
second law of thermodynamics
This
site shows that some ancient questions about "things going wrong"
in our lives have surprisingly simple answers in modern basic chemistry
(even things happening to us which cause that painful cry of "Why
me?")
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Microelectrode
Techniques
The full text of this vital textbook - 450 pages of practical
and theoretical discussion and teaching materials on the latest developments
in electrophysiology. The first Plymouth 'Microelectrode Techniques'
workshop was held in April 1984. Interest in this subject area was very high
and the workshop was greatly oversubscribed. The workshop has been updated
and repeated many times since, and this handbook arose out of the need to
further disseminate the knowledge assembled by the leading experts in this
field. This year's course (1999) is being held in September, and you can
find full details here. |
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Introduction
to Macromolecular Simulation
The
purpose of this tutorial is to introduce several popular numerical
techniques used to simulate the structure and dynamics of biomolecules. The
discussion is confined to simulation methods that apply classical mechanics
to biological systems, although some quantum theory is presented to quantify
some shortcomings of classical approximations. Molecular dynamics (MD)
simulation, Langevin dynamics (LD) simulation, Monte Carlo (MC) simulation,
and normal mode analysis are among the methods surveyed here. |
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METABOLOMICS
IN ABERYSTWYTH
Whilst there is much current interest in the genome-wide
analysis of cells at the level of transcription (to define the
'transcriptome') and translation (to define the 'proteome'), the third level
of analysis, that of the 'metabolome', has been curiously unexplored to
date. The term 'metabolome' refers to the entire complement of all the small
molecular weight metabolites inside a cell suspension (or other sample) of
interest. It is likely that measurement of the metabolome in different
physiological states will in fact be much more discriminating for the
purposes of functional genomics. |
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Computers
for Biochemists & Molecular Biologists. Course of lectures
This course is being developed by B. Tracy Nixon (btn1@psu.edu).
Two prior versions were offered in the Fall of 1995, 1996 and 1997. It is
being offered again in the Fall of 1998 in two sections. |
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Simulation
of metabolic systems (by Pedro Mendes)
Work in the following areas: 1. Construction of a biochemical
kinetics simulation program (GEPASI). 2. Usage of simulation to study
protein-protein interactions, more specifically metabolite channelling 3.
simulation of heterogeneous spatio-temporal biochemical models. Another area
actively involved is Metabolic Control Analysis. MCA can be used both to
analyze experimental results and to characterize results from simulations. |
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GEPASI
(developed by Pedro
Mendes)
a user- friendly MS- Windows computer program to simulate the dynamics of
biochemical systems, with an emphasis on the steady- state properties of
pathways containing enzymes that interact by transferring their intermediate
metabolite directly (metabolic channelling). |
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Mitochondria
Studies
The experiments on mitochondria, described here, were
designed to augment the student's understanding of how mitochondria
function, while providing a hands-on experience. The recommended studies
have been carried out successfully on preparations from rat liver. |
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3D
model gallery
You can find here Rat Liver Mitochondrion 3D model and
several other interesting models |
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Lectures
on biological energy conversion (Biophysics 354)
Introduces
and explores the major mechanisms of energy conversion in biology, with
particular emphasis on respiratory and photosynthetic bioenergetics, and the
physic-chemical tools required to describe these processes. |
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Oxidative
Phosphorylation Home Page
These
pages describe how mitochondria use the energy from substrate oxidation to
drive the synthesis of ATP from ADP and inorganic phosphate. The system also
powers many cellular transport processes.
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bc1
complex site
This
site contains information, links, pictures, and down-loadable materials
based on research on the bc1 complex. This group of electron
transfer enzymes,- generally known as bc1 complexes in
mitochondria, bacterial respiratory chains and photosynthetic bacteria, or b6f
complexes in the photosynthetic chains of oxygenic photosynthesis,- carries
the main flux of energy through the biosphere |
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Complex
I Home Page
The
purpose of this site is to provide general information regarding complex I
(NADH quinone oxidoreductase) to researchers in the field of bioenergetics
as well as to those who are simply curious about what this enzyme complex
does. |
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Brdiczka
Laboratory
University
of Konstanz, Faculty of Biology, Brdiczka Laboratory. Scientific work
concentrates on: Energy transfer and signal transduction between
mitochondria and cytosol. On this site you can find some great related
educational software. |
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Mitochondrial
Disease Information
The United Mitochondrial Disease Foundation. Glossary
of Terms. Literature Reviews. Mitochondria and Disease. Mitochondrial
Disease Descriptions. Mitochondrial Disease Publications by UMDF. UMDF
Medical Article Database and Library. |
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Molecular
biology Hypertextbook
This
hypertextbook is designed to supplement the course materials of 7.01 (MIT
Introductory Biology) and give you additional tools to learn introductory
molecular biology. The 7.01 hypertextbook is organized in a very
straightforward manner and contains a variety of components designed to be
used independently or together to facilitate your understanding of
introductory molecular biology |
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Molecular
Biology and Cellular Regulation course
1999. Instructor: Dr. Frank Pugh |
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Biotechnology
Areas
Brief description of various Biotechnology areas (with links
to some companies): Biotechnology (General), Molecular Biology, Sequence
Search and Analysis, Software, Tutorials, Biochemistry, Protein
Purification, Tutorials, Software, Biophysics, Photosynthesis, Scientific
Analysis/Modeling, Molecular Modeling, Software, Bioinformatics, Sequence
Search and Analysis, Structure Search and Analysis |