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Free radicals, oxidative stress and antioxidant system

Free radicals and prooxidants effect on PT

Cassarino DS, Bennett JP Jr. / An evaluation of the role of mitochondria in neurodegenerative diseases: mitochondrial mutations and oxidative pathology, protective nuclear responses, and cell death in neurodegeneration. // Brain Res Brain Res Rev, - 1999 Jan, - 29. - pp.1-25.    [MEDLINE]

Connern CP, Halestrap AP. / Chaotropic agents and increased matrix volume enhance binding of mitochondrial cyclophilin to the inner mitochondrial membrane and sensitize the mitochondrial permeability transition to [Ca2+]. // Biochemistry, - 1996 Jun 25, - 35. - pp.8172-80.    [MEDLINE]

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Lenaz G, Bovina C, Formiggini G, Castelli GP. / Mitochondria, oxidative stress, and antioxidant defences. // Acta Biochim Pol, - 1999, - 46. - pp.1-21.    [MEDLINE]

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Yang JC , Cortopassi GA. / Induction of the mitochondrial permeability transition causes release of the apoptogenic factor cytochrome c [In Process Citation] // Free Radic Biol Med, - 1998 Mar 1, - 24. - pp.624-31.    [MEDLINE]

Free radicals effect on mitochondria metabolism

Brookes PS , Land JM , Clark JB , Heales SJ. / Peroxynitrite and brain mitochondria: evidence for increased proton leak. // J Neurochem, - 1998 May, - 70. - pp.2195-202.    [MEDLINE]

Marshansky V. / Organic hydroperoxides at high concentrations cause energization and activation of ATP synthesis in mitochondria. // J Biol Chem, - 1989 Mar 5, - 264. - pp.3670-3.    [MEDLINE]

Toyo-oka T, Arisaka H, Sanma H, Shin WS, Dan Y, Sugimoto T. / Synergistic deleterious effect of micromolar Ca ions and free radicals on respiratory function of heart mitochondria at cytochrome C and its salvage trial. // Biochem Biophys Res Commun, - 1989 Sep 29, - 163. - pp.1397-403.    [MEDLINE]

Vlessis AA, Widener LL, Bartos D. / Effect of peroxide, sodium, and calcium on brain mitochondrial respiration in vitro: potential role in cerebral ischemia and reperfusion. // J Neurochem, - 1990 Apr, - 54. - pp.1412-8.    [MEDLINE]

Wiswedel I , Trumper L , Schild L , Augustin W. / Injury of mitochondrial respiration and membrane potential during iron/ascorbate-induced peroxidation. // Biochim Biophys Acta, - 1988 Jun 15, - 934. - pp.80-6.    [MEDLINE]

Free radicals generation

Brookes PS , Land JM , Clark JB , Heales SJ. / Peroxynitrite and brain mitochondria: evidence for increased proton leak. // J Neurochem, - 1998 May, - 70. - pp.2195-202.    [MEDLINE]

Das DK, George A, Liu XK, Rao PS. / Detection of hydroxyl radical in the mitochondria of ischemic-reperfused myocardium by trapping with salicylate. // Biochem Biophys Res Commun, - 1989 Dec 29, - 165. - pp.1004-9.    [MEDLINE]

Lenaz G, Bovina C, Formiggini G, Castelli GP. / Mitochondria, oxidative stress, and antioxidant defences. // Acta Biochim Pol, - 1999, - 46. - pp.1-21.    [MEDLINE]

McCord JM. / Free radicals and myocardial ischemia: overview and outlook. // Free Radic Biol Med, - 1988, - 4. - pp.9-14.    [MEDLINE]

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Rodrigues CM , Fan G , Wong PY , Kren BT , Steer CJ. / Ursodeoxycholic acid may inhibit deoxycholic acid-induced apoptosis by modulating mitochondrial transmembrane potential and reactive oxygen species production [In Process Citation] // Mol Med, - 1998 Mar, - 4. - pp.165-78.    [MEDLINE]

Sandri G , Panfili E , Ernster L. / Hydrogen peroxide production by monoamine oxidase in isolated rat-brain mitochondria: its effect on glutathione levels and Ca2+ efflux. // Biochim Biophys Acta, - 1990 Sep 14, - 1035. - pp.300-5.    [MEDLINE]

Sokol RJ, Devereaux M, Mierau GW, Hambidge KM, Shikes RH. / Oxidant injury to hepatic mitochondrial lipids in rats with dietary copper overload. Modification by vitamin E deficiency. // Gastroenterology, - 1990 Oct, - 99. - pp.1061-71.    [MEDLINE]

Antioxidant system

Brookes PS , Land JM , Clark JB , Heales SJ. / Peroxynitrite and brain mitochondria: evidence for increased proton leak. // J Neurochem, - 1998 May, - 70. - pp.2195-202.    [MEDLINE]

Kurosawa K, Shibata H, Hayashi N, Sato N, Kamada T, Tagawa K. / Kinetics of hydroperoxide degradation by NADP-glutathione system in mitochondria. // J Biochem (Tokyo), - 1990 Jul, - 108. - pp.9-16.    [MEDLINE]

Lenaz G, Bovina C, Formiggini G, Castelli GP. / Mitochondria, oxidative stress, and antioxidant defences. // Acta Biochim Pol, - 1999, - 46. - pp.1-21.    [MEDLINE]

Lotscher HR, Winterhalter KH, Carafoli E, Richter C. / Hydroperoxides can modulate the redox state of pyridine nucleotides and the calcium balance in rat liver mitochondria. // Proc Natl Acad Sci U S A, - 1979 Sep, - 76. - pp.4340-4.    [MEDLINE]

Martensson J, Meister A. / Mitochondrial damage in muscle occurs after marked depletion of glutathione and is prevented by giving glutathione monoester. // Proc Natl Acad Sci U S A, - 1989 Jan, - 86. - pp.471-5.    [MEDLINE]

Panfili E, Sandri G, Ernster L. / Distribution of glutathione peroxidases and glutathione reductase in rat brain mitochondria. // FEBS Lett, - 1991 Sep 23, - 290. - pp.35-7.    [MEDLINE]

Sandri G , Panfili E , Ernster L. / Hydrogen peroxide production by monoamine oxidase in isolated rat-brain mitochondria: its effect on glutathione levels and Ca2+ efflux. // Biochim Biophys Acta, - 1990 Sep 14, - 1035. - pp.300-5.    [MEDLINE]

 

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