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MATHEMATICAL MODELING OF THE PART OF MITOCHONDRIAL RESPIRATORY CHAIN IN FRAMES OF PROTON-CHEMICAL HYPOTHESIS.

A.G. Anishkin
Biology Research Institute of Kharkov State University.

Summary

he dependence of ATP-synthesis and mitochondria respiration rates on membrane potential is analyzed in frames of proton-chemical hypothesis of oxidative phosphorylation. The mathematical and electrical models of the part of respiratory chain are proposed. Computer analysis of the mathematical model allowed to obtain the theoretical dependence of the rates of ATP synthesis and of the respiration on membrane potential that are in good qualitative agreement with experimental data, contradicting chemiosmotic hypothesis.