Andrey G. Anishkin, Ph.D.

Curriculum Vitae

Address

Department of Biology,
University of Maryland
College Park, MD 20742
Telephone:   (310) 405-6923.
Fax:              (310) 314-9358
                +1 (810) 958-77-65

Web page:  https://mitoart.tripod.com/

Education

1994. M.Sc. in Biophysics, 1st Class Honors Degree, Kharkov National University, Kharkov, Ukraine.
          Thesis: "Regulation of the inner membrane permeability in the dynamics of
           large-scale mitochondria swelling"

1999. Ph.D. in Biophysics. Biology Research Institute of Kharkov National University, Kharkov, Ukraine.
          Dissertation: "Mathematical description and computer analysis of proton-chemical and
          chemiosmotic mechanisms of energy coupling"

Research Experience

1991 - 1994. Undergraduate research assistant at Molecular and Applied Biophysics Department,
                      Kharkov National University, Kharkov, Ukraine.
1994 - 1995. Graduate research assistant at General and Medical Biophysics Department, Fundamental
                     Medicine Faculty, Kharkov National University, Kharkov, Ukraine.
                     Research area: Mitochondrial permeability transition pore.
                     Methods used:  Optical methods of mitochondria swelling registration
                                                Fluorescent spectroscopy of pyridine nucleotides contents
                                                Polarographic measurement of mitochondria respiration rate
                                                Differential spectroscopy of mitochondrial cytochromes
                                                Methods of continuous change of media composition

1994 - 1997.  Post-graduate in biophysics. Kharkov National University, Kharkov, Ukraine.

1995 - 2000.  Research fellow. Membrane Biophysics Department. Biology Research Institute of
                     Kharkov National University, Kharkov, Ukraine.
                     Research area: Energy coupling mechanism in biological membranes (theoretical study).
                     Methods used:  Metabolic control analysis methods
                                                Equivalent electric circuits method
                                                Mathematical models creation and analysis in MathCAD 6.0 - 8.0
                                                Programming, models analysis and optimization in Q-basic, Pascal, Visual
                                                   Basic 4.0 - 5.0, MatLab 5.3.
                                                Databases creation in MS Access 97 - 2000.

2000 - pres.  Faculty research assistant. Department of Biology, University of Maryland,
                     College Park, Maryland, US.
                     Research area: Molecular mechanism of mechanosensing in MscL and MscS channels.
                     Methods used: Patch-clamp studies

Teaching Experience

1995. Lecturer in bioenergetics at the Faculty of Fundamental Medicine of Kharkov National University,
          Kharkov, Ukraine.

Honors and Awards

1991, 1992, 1993. The winner of a contest of students term papers at Molecular and Applied
           Biophysics Department, Kharkov National University, Kharkov, Ukraine.

1992. Alexander S. Popov scholarship winner.

Membership

• Ukrainian Biochemical Society
• Ukrainian Biophysical Society
• Ukrainian Gerontological Society
• Mitochondria Interest Group

Research Interests

• Molecular mechanism of membrane channels mechanosensing
• Mechanism and regulation of permeability transition pore generation in the inner mitochondrial membrane
• Simulation of permeability transition dynamics
• Energy coupling mechanism
• F-type ATP synthases structure and functioning
• Regulation of electron transport in RedOx chains
• Mathematical modeling of energy coupling systems

Publications

Papers

• A.G.Anishkin.
  MATHEMATICAL MODELING OF THE PART OF MITOCHONDRIAL RESPIRATORY CHAIN IN FRAMES OF PROTON-CHEMICAL HYPOTHESIS.
  Dop. Nacion. Akad. Nauk. Ukr., - 1998, - N5, - p. 183-189. (In Russian, abstract in English)
• A.G. Anishkin, V.V. Lemeshko.
  THEORETICAL DEPENDENCE OF PHOSPHATE POTENTIAL ON MAGNITUDE OF PROTONMOTIVE FORCE FOR TWO-ELECTRON PROTON-CHEMICAL COUPLING POINT MODEL.
  Visnik Harkivskogo Universitetu N422. Biofizichniy visnik, v. 2. - 1998. -p. 74-77. (In English)   
• V.V.Lemeshko, A.G.Anishkin.
  THE MATHEMATICAL MODELING OF ENERGY COUPLING IN MITOCHONDRIA IN FRAMES OF PROTON-CHEMICAL HYPOTHESIS.
  Biofizika, - 1998, - N 2, - p. 308-314. (In Russian, also available in English)
• A.G.Anishkin.
  MODELING OF COMBINATION OF PROTON-CHEMICAL AND CHEMIOSMOTIC ENERGY COUPLING MECHANISMS BY METHOD OF EQUIVALENT ELECTRIC CIRCUITS
  Biologicheskiy vestnik, 1997, - v.1, N1, - p.107-111. (In Russian, abstract in English)
• Lemeshko V.V., Anishkin A.G.
  Computer analysis of proton-chemical hypothesis of energy coupling in biomembranes.
  Revista Colombiana de Fisica, 1997 ( in press).
  (In English)
• V.V.Lemeshko, A.G.Anishkin.
  THE MATHEMATICAL MODELING OF PROTON-CHEMICAL POINT OF COUPLING OF ATP SYNTHESIS WITH ELECTRONIC TRANSPORT IN BIOMEMBRANES
  School of Fundam. Medicine Journal. - 1996, - V. 2, N2, - P. 4-9. (In English)

Conferences Proceedings

• V.V.Lemeshko, A.G.Anishkin.
  ELECTRO-MATHEMATICAL MODELING OF FREE-RADICAL MECHANISM OF PROTON-CHEMICAL COUPLING.
  Thesis of II congress of Ukr. Biophyz. Soc., 29 May, Kharkov, Ukraine. - 3 June, -1998, - p. 136. (Lecture In Russian)
• V.V.Lemeshko, A.G.Anishkin.
  COMPUTER ANALYSIS OF PROTON-CHEMICAL HYPOTHESIS OF ENERGY COUPLING IN BIOMEMBRANES.
  XVII Congreso Nacional de Fisica. Primer Congreso Nacional de Biofisica. Medellin, Colombia. 23-27 de junio, 1997,. - P.116-117. (In English)
• V.V.Lemeshko, A.G.Anishkin.
  MATHEMATICAL MODELING OF ENERGY COUPLING IN MITOCHONDRIA IN FRAMES OF PROTON-CHEMICAL HYPOTHESIS.
  Thesis of II congress of Belor. Soc. Photobiol. Biophys., "Molecular and Cellular Fundamentals of Biosystems Functioning". Minsk, Belorussia. - 25-27 June, 1996. - P. 207. (Lecture in Russian).

References

Available upon request.